Research

Current and Continuing Research

C.G. Evans, J. O'Brien, E. Winfree, A. Murugan, Pattern recognition in the nucleation kinetics of molecular self-assembly at FNANO 2020. (In-person conference cancelled; online talk available on YouTube.)
C.G. Evans, J. O'Brien, E. Winfree, A. Murugan, Kinetic control of spontaneous nucleation in uniquely-addressed multifarious self-assembly at DNA25, Aug 2019.
C.G. Evans, E. Winfree, Optimizing Tile Set Size While Preserving Proofreading with a DNA Self-assembly Compiler. DNA24, LNCS 11145, pp. 37-54. 2018.
C.G. Evans, E. Winfree. Physical principles for DNA tile self-assembly. Chemical Society Reviews, 46(12), pp. 3808-3829. 2017.

stickydesign: a short (sticky end/toehold) DNA sequence design package.
alhambra: a Python package for DNA tile system design.
Xgrow: a kinetic Tile Assembly Model simulator.
rgrow: a modular kinetic Tile Assembly Model simulator for fast, short simulations (prerelease).
scikits-bootstrap: a Python package for bootstrap statistics.

The physics of α-synuclein self-assembly into aggregates, and its impacts on Multiple Systems Atrophy.
Potential links between mitochondrial disorders and Multiple Systems Atrophy (2007-2008, research with Dr. Richard Haas and Dr. Robert Naviaux at UCSD, 2007).
Synthetic construction of designed mitochondrial genomes (2007-2009).
Research with Dr. Clifford Shults at UCSD into potential treatments for Multiple Systems Atrophy, through the Parkinson's Disease Research Fund. (2006)
High-throughput assays of synthesized potential treatments for Multiple Systems Atrophy. (2006-2010)